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BRAINS-TBI

Biomarkers for RAtional Investigation for Neurological decision Support in TBI: BRaINS-TBI

Mild brain injury ≥ 16 years of age Blood test

Study aim

Looking at whether a new blood test can help decide whether a patient with a head injury needs a CT head scan or not

Inclusion Criteria

  • ≥ 16 years of age
  • Glasgow Coma Score 13, 14, or 15
  • Presentation within 24 hours of sustaining a head injury
  • Meet criteria to be assessed for consideration of a head CT using NICE NG232 clinical decision support tool (CDST)
  • Patients with a prior history of TBI which required clinical assessment but occurred more than 1 year prior may still be included

Exclusion Criteria

  • Participant without capacity and no available patient legal representative or professional consultee available
  • Participant with capacity unwilling to provide informed consent
  • Unable to adequately understand written and verbal English for consent and assessments unless an appropriate translator is available.

Enrollment conflicts

  • Yes - the Research Team will be able to advise

Step-by-step recruitment guide

Standard working hours (09:00 – 17:00)
1 Contact the ED Research Team when an eligible patient arrives in the ED — send a message via Epic chat to "ED Research Team" or phone 217907.
2 The ED Research Team will see the patient to arrange consent and randomisation.
Out of hours & weekends
X The trial is currently only recruiting within the working hours of the Research Team

Further information